6q Probe (6q22)
-
Price:
Negotiable
- minimum:
- Total supply:
-
Delivery term:
The date of payment from buyers deliver within days
-
seat:
Hubei
-
Validity to:
Long-term effective
-
Last update:
2018-07-09 06:01
-
Browse the number:
385
Company Profile
Wuhan Healthcare Biotechnology Co.,LtdBy certification [File Integrity]
Contact:kanglu(Mr.)
Email:
Telephone:
Phone:
Area:Hubei
Address:Hubei
Website:http://www.health-carebiotech.com/ http://kanglu.sdmfny.com/
Product Details
ROS1 Gene Break Apart Rearrangement Detection Probe
◆Product Advantages
1.Fleetness: Tissue probe hybridization time: 2 hours. Cell probe hybridization time: 1 hour.
2.Accuracy: Less no◆n-specific background staining (dyeing). Increase difficult samples detection rate.
3.Reproducibility: Different laboratories test results are highly reproducible.
◆Probe Description
ROS1 gene break-apart rearrangement probe uses orange-red dye to mark the ROS1 gene 5' end region and green dye to mark ROS1 gene 3' end region. The ROS1 gene break-apart rearrangement can detect all ROS1 gene rearrangements, avoiding the missed diagnosis caused by a single fusion gene.
◆Detection Significance
ROS1 gene break-apart rearrangement occurs mostly in young, non-smoking lung adenocarcinoma patients. ROS1 rearrangements are different from other mutations such as EGFR, KRAS and ALK. The positive rate of ROS1 rearrangement is about 1.5%, and ROS1 rearrangement positive adenocarcinoma is poorly differentiated. ROS1 break-apart rearrangement positive patients are sensitive to XALKORI (Crizotinib) drugs.
◆Size Specifications
◆References
Rimkunas VM, et al. (2012) Clin Cancer Res 18: 4449-57.
Suehara Y, et al. (2012) Clin Cancer Res 18: 6599-608.
Takeuchi K, et al. (2012) Nat Med 18: 378-81.
http://www.health-carebiotech.com/